> ## Documentation Index
> Fetch the complete documentation index at: https://docs.drugs.locusmedical.fr/llms.txt
> Use this file to discover all available pages before exploring further.

# A3. Fiche structurée d'une spécialité



## OpenAPI

````yaml /openapi.json get /v1/specialites/{cis}
openapi: 3.1.0
info:
  title: Locus Drugs, API LAP v1
  description: >-
    API de la base médicamenteuse Locus Drugs : surface A (référentiel, agrément
    HAS, charte de qualité des BdM v3) et surface B (contrôles de prescription,
    dispositif médical).


    Spécifiée en salle blanche, à partir des seuls documents publics de la HAS
    (référentiel LAP ambulatoire v2021.02, charte v3, dossier d'agrément,
    structuration de la posologie) et du décret n° 2019-856. Aucune
    documentation d'éditeur de base tiers n'a été consultée.


    Chaque route déclare les critères qu'elle couvre dans `x-criteres`. Chaque
    réponse porte l'édition de la base dans `X-Locus-Drugs-Edition` ;
    `?edition=` rejoue une édition passée.
  contact:
    name: Locus
    url: https://locusmedical.fr/
  version: 1.0.0
servers:
  - url: https://drugs.locusmedical.fr
    description: Locus Drugs
security:
  - editeur: []
    abonne: []
paths:
  /v1/specialites/{cis}:
    get:
      tags:
        - A. Référentiel
      summary: A3. Fiche structurée d'une spécialité
      operationId: specialite_v1_specialites__cis__get
      parameters:
        - name: cis
          in: path
          required: true
          schema:
            type: string
            pattern: ^\d{8}$
            title: Cis
            description: Code CIS (ANSM), 8 chiffres.
          description: Code CIS (ANSM), 8 chiffres.
      responses:
        '200':
          description: Successful Response
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/Specialite'
        '422':
          description: Validation Error
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
components:
  schemas:
    Specialite:
      properties:
        edition:
          $ref: '#/components/schemas/Edition'
        cis:
          type: string
          pattern: ^\d{8}$
          title: Cis
          description: Code CIS (ANSM), 8 chiffres.
        libelle:
          type: string
          title: Libelle
        dc:
          type: string
          title: Dc
        dc_id:
          anyOf:
            - type: string
            - type: 'null'
          title: Dc Id
          description: Médicament virtuel (A5) auquel elle appartient.
        codes:
          $ref: '#/components/schemas/Codes'
        composition:
          $ref: '#/components/schemas/Composition'
        formes_unites:
          $ref: '#/components/schemas/FormesUnites'
        statuts:
          $ref: '#/components/schemas/StatutsReglementaires'
        substitution:
          $ref: '#/components/schemas/Substitution'
        vie_administrative:
          $ref: '#/components/schemas/VieAdministrative'
        economie:
          items:
            $ref: '#/components/schemas/EconomiePresentation'
          type: array
          title: Economie
          default: []
        evaluation_has:
          $ref: '#/components/schemas/EvaluationHas'
          default:
            avis: []
            sources: []
        securite:
          $ref: '#/components/schemas/Securite'
          default:
            pgr: false
            marr: []
            informations_en_cours: []
            sources: []
        documents:
          items:
            $ref: '#/components/schemas/Document'
          type: array
          title: Documents
          default: []
        niveau_information:
          $ref: '#/components/schemas/NiveauInformation'
        sources:
          items:
            $ref: '#/components/schemas/Source'
          type: array
          title: Sources
          default: []
      additionalProperties: false
      type: object
      required:
        - edition
        - cis
        - libelle
        - dc
        - codes
        - composition
        - formes_unites
        - statuts
        - substitution
        - vie_administrative
        - niveau_information
      title: Specialite
      description: A3. La fiche structurée d'une spécialité (CH 4).
    HTTPValidationError:
      properties:
        detail:
          items:
            $ref: '#/components/schemas/ValidationError'
          type: array
          title: Detail
      type: object
      title: HTTPValidationError
    Edition:
      properties:
        id:
          type: string
          title: Id
          description: Identifiant d'édition, « 2026.10.2 » ; monotone.
        date:
          type: string
          format: date
          title: Date
        hors_cycle:
          type: boolean
          title: Hors Cycle
          description: Publication hors cycle pour une information urgente (CH 9).
          default: false
        motif:
          anyOf:
            - type: string
            - type: 'null'
          title: Motif
      additionalProperties: false
      type: object
      required:
        - id
        - date
      title: Edition
      description: 'Une édition de la base : identifiant et date (CH 11, R-LAP 111).'
    Codes:
      properties:
        cis:
          type: string
          pattern: ^\d{8}$
          title: Cis
          description: Code CIS (ANSM), 8 chiffres.
        cip13:
          items:
            type: string
            pattern: ^\d{13}$
            description: Code CIP13, 13 chiffres.
          type: array
          title: Cip13
          description: Présentations actuelles.
          default: []
        cip13_historiques:
          items:
            type: string
            pattern: ^\d{13}$
            description: Code CIP13, 13 chiffres.
          type: array
          title: Cip13 Historiques
          default: []
        ucd:
          items:
            type: string
          type: array
          title: Ucd
          default: []
        medicabase:
          anyOf:
            - type: string
            - type: 'null'
          title: Medicabase
        atc:
          anyOf:
            - type: string
            - type: 'null'
          title: Atc
        substances_sms:
          items:
            type: string
          type: array
          title: Substances Sms
          description: Codes SMS (EMA) des substances actives.
          default: []
        forme_edqm:
          anyOf:
            - $ref: '#/components/schemas/Terme'
            - type: 'null'
        voies_edqm:
          items:
            $ref: '#/components/schemas/Terme'
          type: array
          title: Voies Edqm
          default: []
        unite_presentation_edqm:
          anyOf:
            - $ref: '#/components/schemas/Terme'
            - type: 'null'
        codes_transitoires_ansm:
          items:
            type: string
          type: array
          title: Codes Transitoires Ansm
          default: []
      additionalProperties: false
      type: object
      required:
        - cis
      title: Codes
    Composition:
      properties:
        actifs:
          items:
            $ref: '#/components/schemas/ComposantActif'
          type: array
          title: Actifs
        excipients:
          items:
            $ref: '#/components/schemas/ExcipientPresent'
          type: array
          title: Excipients
          default: []
        classes_allergie_croisee:
          items:
            $ref: '#/components/schemas/Terme'
          type: array
          title: Classes Allergie Croisee
          description: Classes servant au contrôle d'allergie croisée (B3).
          default: []
      additionalProperties: false
      type: object
      required:
        - actifs
      title: Composition
    FormesUnites:
      properties:
        forme:
          anyOf:
            - type: string
            - type: 'null'
          title: Forme
        voies:
          items:
            type: string
          type: array
          title: Voies
          default: []
        unites_posologie:
          items:
            type: string
            maxLength: 40
            minLength: 1
            description: 'Unité UCUM (CH 18) : mg, g, ug, mL, {comprime}, {gelule}, [iU]…'
          type: array
          title: Unites Posologie
          description: >-
            Unités de quantité utilisables pour la posologie (celles du RCP) :
            {comprime}, mg, mL, {goutte}…
          default: []
        divisibilite:
          anyOf:
            - $ref: '#/components/schemas/Divisibilite'
            - type: 'null'
        teneur_goutte:
          anyOf:
            - $ref: '#/components/schemas/Quantite'
            - type: 'null'
          description: Masse de substance par goutte.
        volume_injectable:
          anyOf:
            - $ref: '#/components/schemas/Quantite'
            - type: 'null'
        solutes_compatibles:
          items:
            type: string
          type: array
          title: Solutes Compatibles
          default: []
        sources:
          items:
            $ref: '#/components/schemas/Source'
          type: array
          title: Sources
          default: []
      additionalProperties: false
      type: object
      title: FormesUnites
    StatutsReglementaires:
      properties:
        liste:
          anyOf:
            - type: string
              enum:
                - I
                - II
                - stupefiant
                - hors_liste
            - type: 'null'
          title: Liste
        assimile_stupefiant:
          type: boolean
          title: Assimile Stupefiant
          default: false
        medicament_exception:
          type: boolean
          title: Medicament Exception
          default: false
        fit_url:
          anyOf:
            - type: string
            - type: 'null'
          title: Fit Url
          description: Fiche d'information thérapeutique du médicament d'exception.
        prescription_restreinte:
          items:
            $ref: '#/components/schemas/PrescriptionRestreinte'
          type: array
          title: Prescription Restreinte
          default: []
        derive_du_sang:
          type: boolean
          title: Derive Du Sang
          default: false
        dopant:
          type: boolean
          title: Dopant
          default: false
        surveillance_renforcee:
          type: boolean
          title: Surveillance Renforcee
          default: false
        mte:
          type: boolean
          title: Mte
          description: Marge thérapeutique étroite (arrêté du 12/11/2019).
          default: false
        mitm:
          type: boolean
          title: Mitm
          description: Médicament d'intérêt thérapeutique majeur.
          default: false
        serialisation:
          type: boolean
          title: Serialisation
          default: false
        dasri:
          type: boolean
          title: Dasri
          default: false
        usage_professionnel:
          type: boolean
          title: Usage Professionnel
          default: false
        duree_max_prescription_jours:
          anyOf:
            - type: integer
            - type: 'null'
          title: Duree Max Prescription Jours
        fractionnement_jours:
          anyOf:
            - type: integer
            - type: 'null'
          title: Fractionnement Jours
        chevauchement_interdit:
          type: boolean
          title: Chevauchement Interdit
          default: false
        ordonnance_securisee:
          type: boolean
          title: Ordonnance Securisee
          default: false
        sources:
          items:
            $ref: '#/components/schemas/Source'
          type: array
          title: Sources
          default: []
      additionalProperties: false
      type: object
      title: StatutsReglementaires
    Substitution:
      properties:
        groupe_generique:
          anyOf:
            - type: string
            - type: 'null'
          title: Groupe Generique
        statut_generique:
          anyOf:
            - type: string
              enum:
                - princeps
                - generique
                - hors_repertoire
            - type: 'null'
          title: Statut Generique
        tfr:
          type: boolean
          title: Tfr
          description: Tarif forfaitaire de responsabilité.
          default: false
        groupe_biosimilaire:
          anyOf:
            - type: string
            - type: 'null'
          title: Groupe Biosimilaire
        statut_biosimilaire:
          anyOf:
            - type: string
              enum:
                - reference
                - biosimilaire
            - type: 'null'
          title: Statut Biosimilaire
        hybride:
          type: boolean
          title: Hybride
          default: false
        sources:
          items:
            $ref: '#/components/schemas/Source'
          type: array
          title: Sources
          default: []
      additionalProperties: false
      type: object
      title: Substitution
    VieAdministrative:
      properties:
        date_amm:
          anyOf:
            - type: string
              format: date
            - type: 'null'
          title: Date Amm
        procedure:
          anyOf:
            - type: string
              enum:
                - nationale
                - centralisee
                - reconnaissance_mutuelle
                - decentralisee
                - adp
                - aip
                - enregistrement_plante
                - autre
            - type: 'null'
          title: Procedure
        titulaire:
          anyOf:
            - type: string
            - type: 'null'
          title: Titulaire
        statut:
          type: string
          enum:
            - commercialise
            - arret
            - suspendu
            - non_commercialise
            - inconnu
          title: Statut
          default: inconnu
        premiere_commercialisation:
          anyOf:
            - type: string
              format: date
            - type: 'null'
          title: Premiere Commercialisation
        arret_commercialisation:
          anyOf:
            - type: string
              format: date
            - type: 'null'
          title: Arret Commercialisation
        motif_arret:
          anyOf:
            - type: string
            - type: 'null'
          title: Motif Arret
        suspension:
          type: boolean
          title: Suspension
          default: false
        acces:
          items:
            $ref: '#/components/schemas/StatutAcces'
          type: array
          title: Acces
          default: []
        sources:
          items:
            $ref: '#/components/schemas/Source'
          type: array
          title: Sources
          default: []
      additionalProperties: false
      type: object
      title: VieAdministrative
    EconomiePresentation:
      properties:
        cip13:
          type: string
          pattern: ^\d{13}$
          title: Cip13
          description: Code CIP13, 13 chiffres.
        libelle:
          type: string
          title: Libelle
        unites:
          anyOf:
            - type: integer
            - type: 'null'
          title: Unites
          description: Nombre d'UCD dans la présentation.
        ucd:
          anyOf:
            - type: string
            - type: 'null'
          title: Ucd
        pfht:
          anyOf:
            - type: number
            - type: 'null'
          title: Pfht
        ppttc:
          anyOf:
            - type: number
            - type: 'null'
          title: Ppttc
        honoraire_dispensation:
          anyOf:
            - type: number
            - type: 'null'
          title: Honoraire Dispensation
        base_remboursement:
          anyOf:
            - type: number
            - type: 'null'
          title: Base Remboursement
        remboursement:
          items:
            $ref: '#/components/schemas/Remboursement'
          type: array
          title: Remboursement
          default: []
        indications_remboursables:
          items:
            type: string
          type: array
          title: Indications Remboursables
          default: []
        eligible_ald:
          anyOf:
            - type: boolean
            - type: 'null'
          title: Eligible Ald
        agrement_collectivites:
          anyOf:
            - type: boolean
            - type: 'null'
          title: Agrement Collectivites
        prix_retrocession:
          anyOf:
            - type: number
            - type: 'null'
          title: Prix Retrocession
        statut:
          type: string
          enum:
            - commercialise
            - arret
            - suspendu
            - non_commercialise
            - inconnu
          title: Statut
          default: inconnu
        commercialisation:
          anyOf:
            - type: string
              format: date
            - type: 'null'
          title: Commercialisation
        arret:
          anyOf:
            - type: string
              format: date
            - type: 'null'
          title: Arret
        sources:
          items:
            $ref: '#/components/schemas/Source'
          type: array
          title: Sources
          default: []
      additionalProperties: false
      type: object
      required:
        - cip13
        - libelle
      title: EconomiePresentation
    EvaluationHas:
      properties:
        avis:
          items:
            $ref: '#/components/schemas/AvisCt'
          type: array
          title: Avis
          default: []
        sources:
          items:
            $ref: '#/components/schemas/Source'
          type: array
          title: Sources
          default: []
      additionalProperties: false
      type: object
      title: EvaluationHas
    Securite:
      properties:
        pgr:
          type: boolean
          title: Pgr
          default: false
        pgr_date:
          anyOf:
            - type: string
              format: date
            - type: 'null'
          title: Pgr Date
        marr:
          items:
            type: string
          type: array
          title: Marr
          description: Mesures additionnelles de réduction du risque (documents).
          default: []
        informations_en_cours:
          items:
            $ref: '#/components/schemas/InformationSecurite'
          type: array
          title: Informations En Cours
          default: []
        sources:
          items:
            $ref: '#/components/schemas/Source'
          type: array
          title: Sources
          default: []
      additionalProperties: false
      type: object
      title: Securite
    Document:
      properties:
        type:
          type: string
          enum:
            - rcp
            - etiquetage
            - notice
            - avis_ct
            - bum
            - put_rd
            - cpc
            - fit
            - autre
          title: Type
        titre:
          type: string
          title: Titre
        url:
          type: string
          title: Url
        date_initiale:
          anyOf:
            - type: string
              format: date
            - type: 'null'
          title: Date Initiale
        dernier_rectificatif:
          anyOf:
            - type: string
              format: date
            - type: 'null'
          title: Dernier Rectificatif
      additionalProperties: false
      type: object
      required:
        - type
        - titre
        - url
      title: Document
    NiveauInformation:
      properties:
        niveau:
          type: string
          enum:
            - complet
            - reduit
          title: Niveau
        motif:
          anyOf:
            - type: string
            - type: 'null'
          title: Motif
          description: AAC, importation parallèle, préparation, RCP non disponible…
      additionalProperties: false
      type: object
      required:
        - niveau
      title: NiveauInformation
      description: >-
        CH 14 : le LAP signale que les contrôles sont moins sûrs sur un produit
        à information réduite.
    Source:
      properties:
        institution:
          type: string
          title: Institution
          description: ANSM, HAS, EMA, Assurance maladie, Légifrance, CRAT…
        document:
          type: string
          title: Document
        url:
          anyOf:
            - type: string
            - type: 'null'
          title: Url
        date_publication:
          anyOf:
            - type: string
              format: date
            - type: 'null'
          title: Date Publication
        date_prise_en_compte:
          anyOf:
            - type: string
              format: date
            - type: 'null'
          title: Date Prise En Compte
          description: >-
            Date à partir de laquelle la base garantit avoir intégré ce
            document.
        institutionnelle:
          type: boolean
          title: Institutionnelle
          description: >-
            Faux pour une source qui n'est pas une institution de référence :
            elle doit alors être distinguée à l'affichage (R-LAP 1, CH 16).
          default: true
        section:
          anyOf:
            - type: string
            - type: 'null'
          title: Section
          description: Section du document (« RCP 4.2 », « tableau 2, ligne 3 »).
        citation:
          anyOf:
            - type: string
              maxLength: 400
            - type: 'null'
          title: Citation
          description: >-
            L'extrait verbatim du document qui justifie la valeur : la preuve
            que l'auditeur veut voir.
      additionalProperties: false
      type: object
      required:
        - institution
        - document
      title: Source
      description: D'où vient une donnée, et depuis quand la base la garantit (CH 16).
    ValidationError:
      properties:
        loc:
          items:
            anyOf:
              - type: string
              - type: integer
          type: array
          title: Location
        msg:
          type: string
          title: Message
        type:
          type: string
          title: Error Type
        input:
          title: Input
        ctx:
          type: object
          title: Context
      type: object
      required:
        - loc
        - msg
        - type
      title: ValidationError
    Terme:
      properties:
        systeme:
          type: string
          title: Systeme
          description: CIM-10, ATC, SNOMED, EDQM, MedDRA…
        code:
          type: string
          title: Code
        libelle:
          anyOf:
            - type: string
            - type: 'null'
          title: Libelle
      additionalProperties: false
      type: object
      required:
        - systeme
        - code
      title: Terme
    ComposantActif:
      properties:
        substance:
          type: string
          title: Substance
          description: Identifiant de substance (code SMS, sinon URI RUIM).
        libelle:
          type: string
          title: Libelle
          description: Substance telle que l'AMM l'écrit (sel).
        base:
          anyOf:
            - type: string
            - type: 'null'
          title: Base
          description: Fraction thérapeutique (base active), si distincte.
        dosage:
          anyOf:
            - $ref: '#/components/schemas/Quantite'
            - type: 'null'
          description: Dosage en base active, UCUM.
        dosage_reference:
          anyOf:
            - type: string
            - type: 'null'
          title: Dosage Reference
          description: « pour un comprimé », « pour 5 mL »…
        dosage_brut:
          anyOf:
            - type: string
            - type: 'null'
          title: Dosage Brut
      additionalProperties: false
      type: object
      required:
        - substance
        - libelle
      title: ComposantActif
    ExcipientPresent:
      properties:
        code:
          anyOf:
            - type: string
            - type: 'null'
          title: Code
        libelle:
          type: string
          title: Libelle
        effet_notoire:
          type: boolean
          title: Effet Notoire
          default: false
        quantite:
          anyOf:
            - $ref: '#/components/schemas/Quantite'
            - type: 'null'
        seuil:
          anyOf:
            - $ref: '#/components/schemas/Quantite'
            - type: 'null'
      additionalProperties: false
      type: object
      required:
        - libelle
      title: ExcipientPresent
    Divisibilite:
      properties:
        fractions:
          items:
            type: number
          type: array
          title: Fractions
          description: 'Fractions équivalentes possibles : 0.5, 0.25.'
          default: []
        masse_plus_petite_fraction:
          anyOf:
            - $ref: '#/components/schemas/Quantite'
            - type: 'null'
      additionalProperties: false
      type: object
      title: Divisibilite
    Quantite:
      properties:
        valeur:
          type: number
          title: Valeur
        unite:
          type: string
          maxLength: 40
          minLength: 1
          title: Unite
          description: 'Unité UCUM (CH 18) : mg, g, ug, mL, {comprime}, {gelule}, [iU]…'
      additionalProperties: false
      type: object
      required:
        - valeur
        - unite
      title: Quantite
    PrescriptionRestreinte:
      properties:
        type:
          type: string
          enum:
            - hospitaliere
            - initiale_hospitaliere
            - reservee_specialistes
            - surveillance_particuliere
          title: Type
        detail:
          anyOf:
            - type: string
            - type: 'null'
          title: Detail
          description: Spécialités habilitées, périodicité du renouvellement…
      additionalProperties: false
      type: object
      required:
        - type
      title: PrescriptionRestreinte
    StatutAcces:
      properties:
        type:
          type: string
          enum:
            - AAP
            - AAC
            - CPC
          title: Type
        debut:
          anyOf:
            - type: string
              format: date
            - type: 'null'
          title: Debut
        fin:
          anyOf:
            - type: string
              format: date
            - type: 'null'
          title: Fin
        indication:
          anyOf:
            - type: string
            - type: 'null'
          title: Indication
      additionalProperties: false
      type: object
      required:
        - type
      title: StatutAcces
    Remboursement:
      properties:
        taux:
          anyOf:
            - type: integer
            - type: 'null'
          title: Taux
          description: Taux en pourcentage (15, 30, 65, 100) ; nul si non remboursable.
        indication:
          anyOf:
            - type: string
            - type: 'null'
          title: Indication
          description: Identifiant d'indication si le taux dépend de l'indication.
        base:
          anyOf:
            - type: number
            - type: 'null'
          title: Base
          description: Base de remboursement en euros, pour une présentation.
      additionalProperties: false
      type: object
      title: Remboursement
    AvisCt:
      properties:
        indication:
          anyOf:
            - type: string
            - type: 'null'
          title: Indication
        smr:
          anyOf:
            - type: string
              enum:
                - important
                - modere
                - faible
                - insuffisant
                - non_precise
            - type: 'null'
          title: Smr
        asmr:
          anyOf:
            - type: string
              enum:
                - I
                - II
                - III
                - IV
                - V
                - non_precise
            - type: 'null'
          title: Asmr
        comparateur:
          anyOf:
            - type: string
            - type: 'null'
          title: Comparateur
        date:
          anyOf:
            - type: string
              format: date
            - type: 'null'
          title: Date
        synthese:
          anyOf:
            - type: string
            - type: 'null'
          title: Synthese
        url:
          anyOf:
            - type: string
            - type: 'null'
          title: Url
      additionalProperties: false
      type: object
      title: AvisCt
    InformationSecurite:
      properties:
        type:
          type: string
          enum:
            - information_securite
            - lettre_professionnels
            - retrait
            - rupture
            - autre
          title: Type
        titre:
          type: string
          title: Titre
        date:
          anyOf:
            - type: string
              format: date
            - type: 'null'
          title: Date
        url:
          anyOf:
            - type: string
            - type: 'null'
          title: Url
      additionalProperties: false
      type: object
      required:
        - type
        - titre
      title: InformationSecurite
  securitySchemes:
    editeur:
      type: apiKey
      in: header
      name: X-Locus-Editeur
      description: Clé d'éditeur de LGC, remise par Locus à la signature du contrat.
    abonne:
      type: apiKey
      in: header
      name: X-Locus-Abonne
      description: >-
        Identifiant de l'abonné (le médecin) chez l'éditeur, par exemple
        rpps:10001234567.

````

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